Mad2 and p27 expression profiles in colorectal cancer and its clinical significance

Table 1 Relationship between expression of Mad2 protein and histological differentiation and lymph node metastasis

Groups	n	Mad2		Positive (%)	P
		+	-
Normal tissue	40	18	22	45
Adenocarcinoma	40	30	10	75	0.01
WD	21	12	9	61.9
MD	11	10	1	99
PD	8	8	0	100	0.041
Lymph node metastasis
Absent	25	16	9	64
Present	15	14	1	88	0.038
Survival period (months)
< 18	12	9	3	75
≥ 18	28	9	19	32	0.013

WD: Well differentiated adenocarcinoma; MD: Moderately differentiated adenocarcinoma; PD: Poorly differentiated adenocarcinoma.