Oral and nasal administration of chicken type II collagen suppresses adjuvant arthritis in rats with intestinal lesions induced by meloxicam

Table 1 Effects of oral and nasal administration of CII on activities of intestinal MPO and DAO in AA rats with or without intragastrical administration of meloxicam (n = 12, mean ± SD)

Groups	DAO (A/mg pro)	MPO (ΔA/(min·g))
Nomal	0.37 ± 0.065	99.47 ± 22.54
AA model	0.26 ± 0.031b	139.80 ± 25.14
AA model + meloxicam	0.15 ± 0.032ab	165.42 ± 21.27b
AA model + oral CII	0.27 ± 0.051	137.15 ± 26.32
AA model + nasal CII	0.28 ± 0.029	132.17 ± 23.18
AA model + meloxicam + oral CII	0.15 ± 0.052ab	159.25 ± 33.36b
AA model + meloxicam + nasal CII	0.16 ± 0.029ab	152.29 ± 27.20b

^aP < 0.05 vs AA model;

^bP < 0.01 vs normal control.