Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2&rsquo;-deoxyuridine

doi:10.3748/wjg.v10.i2.172

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Jan 15, 2004 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Jan 15, 2004; 10(2): 172-176
Published online Jan 15, 2004. doi: 10.3748/wjg.v10.i2.172

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Figure 2 Linear regression for the sensitivity to FdUrd as a function of TS mRNA level (FdUrd-IC50 = 7. 89TS mRNA+4.77, r = 0.81, P = 0.028). Scatter plot shows the corrlation between TS mRNA levels and IC50 of FdUrd.

Citation: Ma T, Zhu ZG, Ji YB, Zhang Y, Yu YY, Liu BY, Yin HR, Lin YZ. Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2’-deoxyuridine. World J Gastroenterol 2004; 10(2): 172-176
URL: https://www.wjgnet.com/1007-9327/full/v10/i2/172.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i2.172