Effects of narcotic analgesic drugs on human Oddi’s sphincter motility

Table 2 Manometric data before and after administration of pethidine in 10 patients (mean ± SD)

	Before pethidine	10 min after pethidine	19 min after pethidine
	administration (n = 10)	administration (n = 10)	administration 20 (n = 10)
Oddi’s sphincter basal pressure (mmHg)	7.06 ± 5.07	11.24 ± 6.11	6.68 ± 4.32
Amplitude of phasic contractions (mmHg)	78.52 ± 40.23	95.65 ± 45.49	70.35 ± 31.67
Frequency of phasic contractions (n/min)	7.31 ± 1.95	6.49 ± 2.81	7.92 ± 2.07
Common bile duct pressure (mmHg)	4.23 ± 2.83	4.70 ± 3.87	3.91 ± 3.36

n represents the number of patients involved in the research.