Tegaserod inhibits noxious rectal distention induced responses and limbic system c-Fos expression in rats with visceral hypersensitivity

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Oct 1, 2004 (publication date) through Jul 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 1, 2004; 10(19): 2836-2841
Published online Oct 1, 2004. doi: 10.3748/wjg.v10.i19.2836

Table 4 Number of c-Fos positive neurons in limbic struc-tures in group C (mean ± SD, n = 8)

	ACC Hippocampus HypoTH Amygdala Thalamus Overall
C-saline	48 ± 8	46 ± 7	36 ± 8	39 ± 7	45 ± 11	214 ± 13
C-Teg1.0	31 ± 7^b	36 ± 8^b	30 ± 9	33 ± 10	34 ± 7^a	164 ± 22^b

^aP < 0.05,

^bP < 0.01 vs C-saline.

Citation: Jiao HM, Xie PY. Tegaserod inhibits noxious rectal distention induced responses and limbic system c-Fos expression in rats with visceral hypersensitivity. World J Gastroenterol 2004; 10(19): 2836-2841
URL: https://www.wjgnet.com/1007-9327/full/v10/i19/2836.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i19.2836