Are gap junction gene connexins 26, 32 and 43 of prognostic values in hepatocellular carcinoma? A prospective study

doi:10.3748/wjg.v10.i19.2785

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Oct 1, 2004 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Oct 1, 2004; 10(19): 2785-2790
Published online Oct 1, 2004. doi: 10.3748/wjg.v10.i19.2785

Table 5 Correlation between clinical and pathological vari-ables and recurrence-related mortality

Parameters	P values
Parameters	UV	MV
Sex	0.888	-
Age (yr)	0.005	0.356
Tumor diameter	0.324	-
(< 3 cm, > 10 cm)
Liver cirrhosis	0.030	0.324
Child-Pugh class	0.548
HBsAg (+)	0.956	-
Anti-HCV (+)	0.785	-
Edmondson Steiner grade	0.000	0.031
Capsule	0.000	0.053
Vascular permeation	0.000	0.048
Daughter nodules	0.039	0.048
Multinodular HCC	0.007	0.324
Tumor necrosis	0.373	-
Tumor hemorrhage	0.356	-
Connexin 26 mRNA	< 0.001	0.031
Connexin 32 mRNA	< 0.001	0.031
Connexin 43 mRNA	0.461	-

UV: Univariate analysis; MV: Multivariate analysis; AFP: Se-rum alpha fetoprotein; HBsAg (+): Positive hepatitis B surface antigen; Anti-HCV(+): Positive hepatitis C virus antibody; Edmondson Steiner grade: Differentiation grades I, II vs III, IV; n.s: Not significant.

Citation: Sheen IS, Jeng KS, Wang PC, Shih SC, Chang WH, Wang HY, Chen CC, Shyung LR. Are gap junction gene connexins 26, 32 and 43 of prognostic values in hepatocellular carcinoma? A prospective study. World J Gastroenterol 2004; 10(19): 2785-2790
URL: https://www.wjgnet.com/1007-9327/full/v10/i19/2785.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i19.2785