Effect of lamivudine treatment on plasma levels of transforming growth factor &beta;1, tissue inhibitor of metalloproteinases-1 and metalloproteinase-1 in patients with chronic hepatitis B

doi:10.3748/wjg.v10.i18.2661

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Sep 15, 2004 (publication date) through Jul 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Sep 15, 2004; 10(18): 2661-2665
Published online Sep 15, 2004. doi: 10.3748/wjg.v10.i18.2661

Table 4 Correlation expressed by r-value and significance be-tween scored degree of hepatic inflammation or fibrosis and plasma levels of TGF-β₁, TIMP-1 and MMP-1 in patients with chronic hepatitis B before lamivudine treatment

	Inflammation		Fibrosis
	Portal	Lobular
TGF-β₁	0.207	0.179	0.391^a
TIMP-1	0.224	0.319	0.620^a
MMP-1	0.009	-0.094	-0.135

^aP < 0.05 vs others.

Citation: Flisiak R, Al-Kadasi H, Jaroszewicz J, Prokopowicz D, Flisiak I. Effect of lamivudine treatment on plasma levels of transforming growth factor β₁, tissue inhibitor of metalloproteinases-1 and metalloproteinase-1 in patients with chronic hepatitis B. World J Gastroenterol 2004; 10(18): 2661-2665
URL: https://www.wjgnet.com/1007-9327/full/v10/i18/2661.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i18.2661