Safety of Curcuma aromatica oil gelatin microspheres administered via hepatic artery

Table 2 Changes in biochemical indices of the dying rats receiving CAO-GMS (mean ± SD)

Group	Nurmber of rats	ALT (U/L)	AST (U/L)	T-BiL (mmol/L)	D-BiL (μmol/L)	BCr (μmol/L)	BUN (mmol/L)
CAO-GMS-1	0	-	-	-	-	-	-
CAO-GMS-2	4	200 ± 54b	805 ± 533b	12.0 ± 5b	46.0 ± 90b	50.0 ± 34b	20.0 ± 12a
CAO-GMS-3	8	186 ± 89b	700 ± 522b	12.4 ± 8.6b	59.0 ± 88b	49.0 ± 43b	20.0 ± 14a
CAO-GMS-4	12	241 ± 289b	715 ± 614b	15.0 ± 19b	78.0 ± 162b	58.0 ± 43b	22.0 ± 13a
GMS	7	232 ± 168b	685 ± 503b	13.8 ± 9.6b	54.0 ± 126b	52.0 ± 36b	20.0 ± 13a
Blank control	0	38 ± 11	278 ± 114	4.5 ± 1.3	3.2 ± 1.6	38.7 ± 3.5	8.6 ± 11.8
CAO	0	-	-	-	-	-	-

^aP < 0.05;

^bP < 0.01 vs blank control.