Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro

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Sep 15, 2004 (publication date) through Nov 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Sep 15, 2004; 10(18): 2628-2631
Published online Sep 15, 2004. doi: 10.3748/wjg.v10.i18.2628

Table 1 Effects of mifepristone on cell proliferation, cell-cycle phase distribution and caspase-3 activity of SGC7901 cells in vitro (mean ± SD)

Concentration (μmol/L)	A_570nm (MTT)	Cell cycle phase distribution (%)			Caspase-3 activity (U)
Concentration (μmol/L)	A_570nm (MTT)	G₀/G₁	S	G₂/M	Caspase-3 activity (U)
0	1.125 ± 0.048	42.25 ± 4.20	35.68 ± 3.98	22.07 ± 3.01	1.28 ± 0.28
2.5	1.024 ± 0.030	49.47 ± 5.68	30.82 ± 4.36	19.71 ± 2.41	2.79 ± 0.36
5	0.896 ± 0.035	52.23 ± 6.22	28.68 ± 3.64	19.01 ± 1.36	5.04 ± 0.29
10	0.678 ± 0.026	65.80 ± 5.63	25.93 ± 3.01	8.27 ± 1.10	9.46 ± 0.20
20	0.548 ± 0.031	77.16 ± 8.25	15.54 ± 2.54	7.29 ± 0.82	15.23 ± 0.41

Citation: Li DQ, Wang ZB, Bai J, Zhao J, Wang Y, Hu K, Du YH. Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro. World J Gastroenterol 2004; 10(18): 2628-2631
URL: https://www.wjgnet.com/1007-9327/full/v10/i18/2628.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i18.2628