Copyright
©The Author(s) 2004.
World J Gastroenterol. Sep 1, 2004; 10(17): 2503-2508
Published online Sep 1, 2004. doi: 10.3748/wjg.v10.i17.2503
Published online Sep 1, 2004. doi: 10.3748/wjg.v10.i17.2503
Table 1 Effect of mild irritants on 500 mL/L ethanol-induced macroscopic lesion formation in gastric mucosa of normal and gastritis rats, and modulation by pretreatment with L-NAME
Pretreatment | Macroscopic lesion areas (mm2) | |
Normal | Gastritis | |
H2O (Control) | 41.17 ± 7.85 | 134.17 ± 19.23d |
200 mL/L EtOH | 2.00 ± 0.93b | 31.33 ± 5.96bf |
50 g/L NaCl | 0 ± 0b | 15.00 ± 3.80bf |
0.3 mol/L HCl | 0 ± 0b | 124.33 ± 20.60f |
L-NAME + H2O | 42.50 ± 10.65 | 125.40 ± 17.75f |
L-NAME + 200 mL/L EtOH | 32.33 ± 9.95a | 98.83 ± 7.22hf |
L-NAME + 50 g/L NaCl | 0 ± 0b | 32.25 ± 7.49bf |
L-NAME + 0.3 mol/L HCl | 0 ± 0b | 104.25 ± 12.20h |
- Citation: Ko JKS, Cho CH, Lam SK. Adaptive cytoprotection through modulation of nitric oxide in ethanol-evoked gastritis. World J Gastroenterol 2004; 10(17): 2503-2508
- URL: https://www.wjgnet.com/1007-9327/full/v10/i17/2503.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i17.2503