Impaired gallbladder motility and delayed orocecal transit contribute to pigment gallstone and biliary sludge formation in β -thalassemia major adults

Figure 2 Time-course of fasting and postprandial gallbladder volumes in 23 β -thalassemia major patients and 70 controls and expressed as mL (panel A) or percent fasting gallbladder volume (panel B). Symbols indicate means, while vertical lines indicate SEM. Patients had impaired gallbladder emptying, with significantly increased fasting and postprandial volumes at each time point (panel A), in spite of similar contraction (panel B), compared to controls.