E-cadherin and calretinin as immunocytochemical markers to differentiate malignant from benign serous effusions

Table 3 Diagnostic values of E-cadherin or/and calretinin ICC for serous effusions

Index	Malignant effusion (%)		Benign effusion (%)
	E-cadherin	E(+) + C(-)	Calretinin	E(-) + C(+)
Sensitivity	85.7	77.1	94.6	86.5
Specificity	91.9	100	88.6	97.1
PV+	90.9	100	89.7	97.0
PV-	87.2	82.2	93.9	87.2
DAR	88.9	88.9	91.7	91.7

E ( + )/E ( - ): E-cadherin ( + )/( - ); C ( + )/C ( - ): Calretinin ( + )/( - ); PV + : ICC-positive predictive value; PV-: ICC-negative predic-tive value; DAR: Accordance rate.