Effect of SNPs in protein kinase Cz gene on gene expression in the reporter gene detection system

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Aug 15, 2004 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 15, 2004; 10(16): 2357-2360
Published online Aug 15, 2004. doi: 10.3748/wjg.v10.i16.2357

Table 2 Transcriptional regulatory activity of each construct of PKCZ in HepG2 cells

Construct	Relative luciferase activity	P
pGL3-promoter	0.3533 ± 0.040
pGL3-rs411021C	0.5167 ± 0.064
pGL3-rs411021T	0.5100 ± 0.102	0.928
pGL3-rs436045A	0.3433 ± 0.051
pGL3-rs436045G	0.3767 ± 0.023	0.363
pGL3-rs427811T	0.6233 ± 0.064^a
pGL3-rs427811G	0.4433 ± 0.068	0.029
pGL3-rs385039A	0.3500 ±0.044
pGL3-rs385039G	0.3467 ±0.015	0.907
pGL3-rs809912A	0.1800 ± 0.017^a
pGL3-rs809912G	0.3033 ± 0.042	0.009

^aP < 0.05 in comparison between construct and pGL3-promoter vector.

Citation: Liu Z, Sun HX, Zhang YW, Li YF, Zuo J, Meng Y, Fang FD. Effect of SNPs in protein kinase Cz gene on gene expression in the reporter gene detection system. World J Gastroenterol 2004; 10(16): 2357-2360
URL: https://www.wjgnet.com/1007-9327/full/v10/i16/2357.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i16.2357