Combined gene therapy of endostatin and interleukin 12 with polyvinylpyrrolidone induces a potent antitumor effect on hepatoma

doi:10.3748/wjg.v10.i15.2195

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Aug 1, 2004 (publication date) through Jul 17, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Aug 1, 2004; 10(15): 2195-2200
Published online Aug 1, 2004. doi: 10.3748/wjg.v10.i15.2195

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Figure 6 Apoptosis of hepatoma cells induced by gene therapy of endostatin and IL-12. Apaptotic tumor cells (TUNEL, 400 × ) treated with pSecES/PVP (11.2 ± 2.3) (B), pmIL-12/PVP (14.4 ± 3.5) (C) or pSecES + pmIL-12/PVP (24.8 ± 4.8) (D) were more than those treated with pcDNA3.1/PVP (1.4 ± 1.7, P < 0.05) (A).

Citation: Li PY, Lin JS, Feng ZH, He YF, Zhou HJ, Ma X, Cai XK, Tian DA. Combined gene therapy of endostatin and interleukin 12 with polyvinylpyrrolidone induces a potent antitumor effect on hepatoma. World J Gastroenterol 2004; 10(15): 2195-2200
URL: https://www.wjgnet.com/1007-9327/full/v10/i15/2195.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i15.2195