Genotype and phylogenetic characterization of hepatitis B virus among multi-ethnic cohort in Hawaii

Table 1 Comparison of clinical backgrounds in carriers with HBV genotypes A, B and C

Features			Genotype n(%)
			A (n = 14)	B (n = 9)	C (n = 38)
Age (mean±SD, yr)			49.1±14.5	46.9±13.0	43.0±11.9
Gender (male:female)			10:4	4:5	21:17
Race	Asian	Mainland Chinese	0(0)	5(33)	10(67)
		Philippine	10(83)	0(0)	2(17)
		Taiwanese	0(0)	2(50)	2(50)
		Hong Kong	0(0)	0(0)	8(100)
		Vietnamese	0(0)	2(40)	3(60)
		Korean	0(0)	0(0)	7(100)
		Japanese	0(0)	0(0)	1(100)
	Micronesian		0(0)	0(0)	3(100)
	Polynesian		1(100)	0(0)	0(0)
	Caucasian		3(60)	0(0)	2(40)
Liver disease		ASC	2(14)	3(33)	9(24)
		CH	10(71)	5(56)	24(63)
		LC	2(14)	1(11)	1(3)
		HCC	0(0)	0(0)	4(11)
		HBeAg (+)	8(57)	3(33)a	26(68)a
Laboratory finding		AST (U/L)	63.3±42.2	56.6±58.7	54.7±81.9
		ALT (U/L)	41.4±31.6	34.8±27.0	37.3±59.7
		ALP (U/L)	359.9±139.4	287.3±140.2	328.0±166.2
		γ -GTP (U/L)	121.0±121.3	55.9±37.2	66.8±103.0

^aP < 0.05 between genotypes B and C. ASC: Asymptomatic carrier; CH: Chronic hepatitis; LC: Liver cirrhosis; HCC: Hepatocellular carcinoma; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; γ -GTP: γ -glutamyl transpeptidase.