Clinicopathologic analysis of esophageal and cardiac cancers and survey of molecular expression on tissue arrays in Chaoshan littoral of China

Table 3 Expression of Erk1/Erk2 in esophageal squamous carcinoma tissue and para-cancerous tissue (%, mean ± SD)

	Normal esophagealsquamous cell (n = 5)	Para-canceroustissue (n = 5)	Grade I (n = 19)	Grade II (n = 34)	Grade III (n = 9)	F	P
Activated ERK1/ERK2	5.10 ± 1.44	76.80 ± 0.14	76.80 ± 0.09	75.80 ± 0.09	69.30 ± 0.14	2.60	0.04

There was marked difference between normal esophageal epithelium and cancer tissues or para-cancerous tissue. But there was no marked difference among para–cancerous tissues and esophageal squamous carcinoma tissues (F = 1.463, P = 0.236).