Contribution of C3d-P28 repeats to enhancement of immune responses against HBV-preS2/S induced by gene immunization

Figure 1 Schematic illustration representation of vector DNA vaccine constructs. A: A synthetic oligonucleotide (ON33) was inserted into the pVAX1 vector by the Hind III and BamH I restriction endonuclease sites. Inserts were cloned into the vector using the BglII and BamH I sites. B: The scheme represents constructs expressing fusions of HBV-preS2/S to variable copies of C3d-P28.