Changes of gut flora and endotoxin in rats with D-galactosamine-induced acute liver failure

Table 1 Degree of hepatic injury and mortality in ALF rats at various time points after injection of GalN

	Group A (n = 10)	Group B (n = 11)	Group C (n = 10)
TP (g/L)	62.6 ± 1.3	48.9 ± 1.2d	51.0 ± 3.1d
Albumin (g/L)	34.3 ± 0.7	27.8 ± 0.7d	30.3 ± 1.1d
Globulin (g/L)	28.6 ± 0.8	21.1 ± 1.1d	21.5 ± 2.6d
ALT (U/L)	60.6 ± 3.3	4798 ± 1114d	3183 ± 1257d
AST (U/L)	138.0 ± 7.5	5032 ± 1067d	2928 ± 843d
AKP (U/L)	272.0 ± 18.6	639 ± 60d	747 ± 133d
TBA (μmol/L)	11.8 ± 2.6	425 ± 33d	262 ± 58da
TBiL(μmol/L)	7.0 ± 0.4	40.6 ± 8.2d	63.2 ± 18.4d
Mortality	NO	8.33% (1/12)	44.44% (8/18)b

Values are expressed as mean ± SE or frequency of occurrence (%).

^aP < 0.05,

^bP < 0.01 vs group B,

^dP < 0.01 vs group A.