Liver Cancer
Copyright ©The Author(s) 2004.
World J Gastroenterol. Jul 1, 2004; 10(13): 1872-1875
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1872
Table 1 Targeting therapy of hscFv25-mTNFα for HCC xenografts
Tumor bulkTumor weightRegression rate ofRegression rate ofCurative
(mm × mm)(mg)tumor bulk (%)tumor weight (%)effect
PBS19 × 511900NR
27 × 78700NR
39 × 45100NR
45 × 32600NR
55 × 43000NR
hscFv2510.8 × 0.5299.296.8PR
-mTNFα22 × 31081.884.0PR
32 × 31581.876.0PR
400100100CR
500100100CR
mTNFα12 × 21187.982.4PR
23 × 32272.764.9PR
32 × 4575.876.0PR
42 × 31081.884.0PR
52 × 31081.884.0PR