Inhibition of Fas/FasL mRNA expression and TNF-α release in concanavalin A-induced liver injury in mice by bicyclol

Figure 6 Effect of bicyclol on Con A induced TNF-α, IFN-γ, Fas and FasL mRNA expression determined by RT-PCR. A: Pho-tograph of ethidium bromide-stained amplification products. Lane 1, molecular mass markers; lane 2 and lane 3, control liver; lane 4 and lane 5, liver 2 h after Con A administration alone; lane 6 and lane 7, liver 2 h after injection of Con A in combination with 200 mg/kg bicyclol. B: Relative band intensity of amplification products compared with Cu/Zn SOD mRNA. Data represent the mean of two lanes. Each lane corresponds to the pooled livers from two mice. ^aP < 0.05 vs Con A alone.