Polymorphisms of interleukin-1B and interleukin-1 receptor antagonist genes in patients with chronic hepatitis B

Table 2 Comparison of IL-1RN intron 2 polymorphism between patients with chronic hepatitis B and controls

Group	n	Frequency of genotypes(%)				Frequency of alleles(%)
		1/1a	1/2b	2/2	1/4	1	2c	4
Patients	190	169 (88.9)	17 (9.0)	1 (0.5)	3 (1.6)	358 (94.2)	19 (5.0)	3 (0.8)
Controls	249	202 (81.1)	42 (16.9)	1 (0.4)	4 (1.6)	450 (90.4)	44 (8.8)	4 (0.8)

Patients vs controls,

^aχ² = 5.03, P = 0.025;

^bχ² = 5.81, P = 0.016;

^cχ² = 4.76, P = 0.029.