Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases

Table 1 Telomerase activity and c-Myc expression in H pylori infected gastric diseases

Diagnosis	Samples number	H pylori infection	Telomerase activity + (%)	P	c-Myc expression + (%)	P
GC	65	+ (44)	38 (86.36)	> 0.05	34 (77.27)	< 0.05a
		- (21)	19 (90.48)		6 (28.57)
CAG with MM	30	+ (18)	3 (16.67)	> 0.05	4 (22.22)	> 0.05
		- (12)	1 (8.33)		1 (8.33)
CAG with SM	42	+ (28)	19 (67.86)	< 0.01b	19 (67.86)	< 0.01d
		- (14)	3 (21.43)		1 (7.14)

χ² test and Fisher’s exact test.

^aP < 0.05 vs c-Myc expression from samples without H pylori infection.

^bP < 0.01 vs telomerase activity from samples without H pylori infection.

^dP < 0.01 vs c-Myc expression from samples without H pylori infection. MM, mild intestinal metaplasia SM, severe intestinal metaplasia.