Structure analysis and expressions of a novel tetratransmembrane protein, lysosoma-associated protein transmembrane 4 β associated with hepatocellular carcinoma

Figure 1 Putative amino-acid sequence of LAPTM4B.

The four transmembrane domains are shadowed with gray color. Two translation initiation sites are thick black. Putative SH3 ligand is indicated by thick underlining. The sequence containing 10 amino acid residues (28aa-37aa or 232aa-241aa) and used as immunogen is wavy underlined. PKC-P, cAMP-P, cGMP-P, CK2-P, Tyr-P: various phosphorylation sites; G: N-glycosylation site; M: myristylation site.