Effects of mu and kappa opioid receptor agonists and antagonists on contraction of isolated colon strips of rats with cathartic colon

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Jun 1, 2004 (publication date) through Nov 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 1, 2004; 10(11): 1672-1674
Published online Jun 1, 2004. doi: 10.3748/wjg.v10.i11.1672

Table 2 Effect of naloxone on electricity-stimulated contrac-tile response of cathartic colon strips (mean ± SD)

Concentration (µmoL)	Basic contraction amplitude without naloxone (mm)	Contraction amplitude with naloxone (mm)
0.05	11.40 ± 0.21	13.18 ± 0.93^b
0.10	11.40 ± 0.21	15.87 ± 0.98^a^b
1.00	11.40 ± 0.21	19.46 ± 1.79^b^d

^aP < 0.05 vs 0.05 µmol/L,

^bP < 0.01 vs without Naloxone,

^dP < 0.01 vs 0.05 µmol/L.

Citation: Liu BH, Mo P, Zhang SB. Effects of mu and kappa opioid receptor agonists and antagonists on contraction of isolated colon strips of rats with cathartic colon. World J Gastroenterol 2004; 10(11): 1672-1674
URL: https://www.wjgnet.com/1007-9327/full/v10/i11/1672.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i11.1672