Polymorphisms at cholesterol 7α-hydroxylase, apolipoproteins B and E and low density lipoprotein receptor genes in patients with gallbladder stone disease

Table 5 Association of CYP7A gene polymorphism with plasma lipids

	Patients		Controls		All
	AA/AC	CC	AA/AC	CC	AA/AC	CC
No.	88	17	219	55	307	72
Triglyceride (mmol/L)	1.25 ± 0.99	1.70 ± 7.77	1.15 ± 0.82	1.36 ± 0.81	1.18 ± 0.87	1.44 ± 1.11
Cholesterol (mmol/L)	4.64 ± 0.95	4.78 ± 0.79	4.84 ± 0.94c	5.16 ± 0.99c	4.78 ± 0.95g	5.07 ± 0.95g
HDL (mmol/L)	1.32 ± 0.37a	1.35 ± 0.32	1.42 ± 0.34a	1.33 ± 0.72	1.39 ± 0.35	1.33 ± 0.32
LDL (mmol/L)	2.56 ± 0.70	2.59 ± 0.45e	2.63 ± 0.72c	2.91 ± 0.72e,c	2.61 ± 0.71g	2.83 ± 0.67g
Apo AI (g/L)	1.34 ± 0.22a	1.36 ± 0.15	1.39 ± 0.18a	1.36 ± 0.20	1.38 ± 0.19	1.36 ± 0.18
Apo B (g/L)	1.00 ± 0.23	1.02 ± 0.15	1.01 ± 0.24c	1.10 ± 0.23c	1.01 ± 0.23g	1.08 ± 0.22g

^aP < 0.05, patients vs controls with AA/AC genotype,

^cP < 0.05, AA/AC vs CC within control group,

^eP < 0.05, patients vs controls with CC genotype,

^gP < 0.05, AA/AC vs CC in all the subjects.