Influence of serum collected from rat perfused with compound Biejiaruangan drug on hepatic stellate cells

Table 5 Influence of each group serum on collagen I of HSC at different time points (A value: mean ± SD)

	N		M		G		Z		D
	A	Male cell area (%)	A	Male cell area (%)	A	Male cell area (%)	A	Male cell area (%)	A	Male cell area (%)
24 h	50.87 ± 9.84	5.49 ± 2.06c	60.63 ± 9.26	4.64 ± 0.26	46.95 ± 5.21	2.90 ± 0.22	44.83 ± 6.97	3.72 ± 0.48	49.46 ± 7.36	3.89 ± 0.79
48 h	270.51 ± 13.56	5.28 ± 0.58	456.78 ± 106.64	5.56 ± 1.83	107.79 ± 17.9	4.45 ± 0.29	115.28 ± 51.85	4.66 ± 1.67	129.35 ± 22.20	4.45 ± 0.50
72 h	507.77 ± 66.38c	11.36 ± 2.39c	800.30 ± 150.39a	15.66 ± 2.34a	300.23 ± 25.80ac	5.25 ± 0.56ac	329.37 ± 45.98ac	6.62 ± 1.33ac	425.38 ± 19.32c	7.99 ± 1.25c

N: Control group; M: Model group; G: High dosage group; Z: Mdium dosage group; D: Low dosage group,

^aP < 0.05 vs normal group;

^cP < 0.05 vs model group.