Perioperative cimetidine administration promotes peripheral blood lymphocytes and tumor infiltrating lymphocytes in patients with gastrointestinal cancer: Results of a randomized controlled clinical trial

Figure 3 Changes in CD₄⁺ cell percentages in perioperative period. A: at randomization; B: before operation; C: on the 2nd postoperative day; and D: on the 10th postoperative day. The difference in CD₄⁺ percentages between treatment and control groups at time points C and D was statistically significant, ^bP < 0.01. The differences in CD₄⁺ percentages on the 10th postoperative day and the randomization day was statistically significant for both treatment and control groups, ^dP < 0.01.