Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles

doi:10.3748/wjg.v10.i1.112

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Jan 1, 2004 (publication date) through Aug 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 1, 2004; 10(1): 112-116
Published online Jan 1, 2004. doi: 10.3748/wjg.v10.i1.112

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Figure 1 Structure of rAAV-ET vector. ITR: AAV-2 inverted terminal repeats, tetO-CMV: tetracycline-inducible promoter including seven repeats of the tetracycline operator inserted upstream of the CMV minimal promoter, mEpo: murine eryth-ropoietin cDNA, (A)n: SV4O bidirectional polyadenylation signal, rtTA: coding sequences for the tetracycline reverse transactivator, LTR: long terminal repeat of the MFG retrovirus construct. The BamHI fragment used as an Epo-specific probe is indicated.

Citation: Chen J, Yang WL, Li G, Qian J, Xue JL, Fu SK, Lu DR. Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles. World J Gastroenterol 2004; 10(1): 112-116
URL: https://www.wjgnet.com/1007-9327/full/v10/i1/112.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i1.112