Magnetic resonance imaging-radiomics evaluation of response to chemotherapy for synchronous liver metastasis of colorectal cancer

Figure 1 Magnetic resonance imaging examinations. A: A 48-year-old female had a synchronous liver metastasis with baseline long diameter of 25.1 mm; B: After chemotherapy, the lesion a had 30.3% decrease in long diameter of 17.5 mm, which belonged to the disease response group for analysis.

Figure 2 The workflow of radiomics signature in differentiating the responses of synchronous liver metastasis patients to chemotherapy. VOI: Volume of interest; GLCM: Gray-level co-occurrence matrices; RLM: Run-length matrices; SZM: Size zone matrices; Rad-score: Radiomics score.

Figure 3 The feature selection method of least absolute shrinkage and selection operator. A total of 12 optimal features were selected.

Figure 4 The nomogram of radiomics-clinical analysis to differentiate patients with disease non-response group from disease response group. The zero in CA19-9 represented normal and one referred to abnormal. DR: Disease response group; Rad-score: Radiomics score.