Endoscopic ultrasound-fine needle biopsies of pancreatic lesions: Prospective study of histology quality using Franseen needle

Figure 1 Study flow diagram.

Figure 2 Endoscopic ultrasound and histology images of two lesions. A: Endoscopic ultrasound-fine needle biopsies (EUS-FNB) of a pancreatic metastasis of a non-small-cell lung cancer; B: The corresponding hematoxylin-eosin (H&E) staining (100 ×), showing a cluster of small tumor cells, high nuclear to cytoplasm ratio and crush artifacts; C: The immunohistochemistry for TTF-1 reactive in the nuclei of tumor. D: EUS-FNB of a pancreatic adenocarcinoma with the Franseen needle; E: The corresponding H&E staining (100 ×), showing characteristic infiltrating glands with tumor cells with nuclear hyperchromatism, pleiomorphism and prominent nucleoli in a cell block.