Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver

Figure 1 Inhibitory effect of hypochlorous acid on hepatic nuclear NTPase activity. ATP and GTP were used as reaction substrates, respectively. Mean ± SD, n = 6. ^aP < 0.05, ^bP < 0.01 com-pared with control.

Figure 2 Effect of taurine on OCl^--induced inhibition of NTPase activity in hepatic nuclei. ATP and GTP were used as reaction substrates, respectively. Mean ± SD, n = 6. ^aP < 0.05, ^bP < 0.01 com-pared with OCl (10^-6 mol/L) group. ^cP < 0.05, ^dP < 0.01 compared with control.

Figure 3 Effects of glutathione on OCl^--induced inhibition of NTPase activity in hepatic nuclei. ATP and GTP were used as reaction substrates, respectively. Mean ± SD, n = 6. ^bP < 0.01 com-pared with control group (OCl^-1 10^-6 mol/L). ^aP < 0.05, ^cP < 0.01 compared with (10^-6 mol/L OCl^-1 + 10^-4 mol/L taurine).