Brief Article
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World J Gastroenterol. Jan 7, 2012; 18(1): 70-78
Published online Jan 7, 2012. doi: 10.3748/wjg.v18.i1.70
Germline promoter hypermethylation of tumor suppressor genes in gastric cancer
Pu-Yuan Wu, Zheng Zhang, Jing-Mei Wang, Wen-Wen Guo, Nong Xiao, Qiong He, Ya-Ping Wang, Yi-Mei Fan
Pu-Yuan Wu, Zheng Zhang, Wen-Wen Guo, Ya-Ping Wang, Yi-Mei Fan, Department of Medical Genetics, Medical School, Nanjing University, Nanjing 210093, Jiangsu Province, China
Pu-Yuan Wu, Zheng Zhang, Wen-Wen Guo, Ya-Ping Wang, Yi-Mei Fan, Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, Jiangsu Province, China
Jing-Mei Wang, Department of Pathology, Drum Tower Hospital Affiliated to Medical School, Nanjing University, Nanjing 210093, Jiangsu Province, China
Nong Xiao, Qiong He, Department of Pathology, Lujiang Hospital, Lujiang, Chaohu 231500, Anhui Province, China
Author contributions: Wu PY and Zhang Z contributed equally to this work; Fan YM conceived and designed the study, and drafted the manuscript; Wu PY, Zhang Z, and Guo WW performed the experiments; Wang JM, Xiao N and He Q contributed to the collection of samples and clinical data; Wang YP reviewed and modified the paper; All of the authors have read and approved the final manuscript.
Supported by The National Natural Science Foundation of China, No. 30972535; the Natural Science Foundation of Jiangsu, China, No. BK2008269; the Fundamental Research Funds for the Central Universities of China, No. 1112021402
Correspondence to: Dr. Yi-Mei Fan, Associate Professor, Department of Medical Genetics, Medical School, Nanjing University, Hankou Road 22, Nanjing 210093, Jiangsu Province, China. ymfan@nju.edu.cn
Telephone: +86-25-83593374 Fax: +86-25-83686559
Received: April 15, 2011
Revised: July 11, 2011
Accepted: July 18, 2011
Published online: January 7, 2012
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