Original Article
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World J Gastroenterol. Dec 28, 2010; 16(48): 6111-6118
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6111
Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats
Ji-Wu Han, Xiao-Rong Zhan, Xin-Yu Li, Bing Xia, Yue-Ying Wang, Jing Zhang, Bao-Xin Li
Ji-Wu Han, Department of Gastroenterology, The 4th Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Xiao-Rong Zhan, Xin-Yu Li, Bing Xia, Yue-Ying Wang, Jing Zhang, Department of Endocrinology, First Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Bao-Xin Li, Department of Pharmacology, State Key Laboratory of Biomedicine and Pharmacology, Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Author contributions: Zhan XR and Li BX designed the research and contributed equally to this work; Han JW, Li XY, Xia B and Wang YY performed the research; Han JW and Zhang J analyzed the data; Han JW, Li XY and Zhan XR wrote the paper.
Supported by The Natural Science Foundation of Heilongjiang Province, No. 2005-13
Correspondence to: Xiao-Rong Zhan, PhD, Professor, Department of Endocrinology, First Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China. xiaorongzhan@sina.com
Telephone: +86-451-53643849 Fax: +86-451-55607786
Received: July 28, 2010
Revised: September 13, 2010
Accepted: September 20, 2010
Published online: December 28, 2010
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