Baishideng Publishing Group

Zeng XW, Hu LF, Cao XL, Yang BR, Wu ZM. Fluctuating course of attention-deficit/hyperactivity disorder across development: Multifactorial influences. World J Psychiatry 2025; 15(8): 107780

"I would like to extend my sincere gratitude to the editors and the entire team behind this publication for their exceptional dedication ..." [Read more]

"I would like to extend my sincere gratitude to the editors and the entire team behind this publication for their exceptional dedication and professionalism throughout the process. From manuscript submission to final production, every step was handled efficiently with clear communication. I particularly appreciate the attention to detail and collaborative spirit demonstrated by all involved, which significantly contributed to the smooth publication of my work. This experience has been highly positive, and I am thoroughly satisfied with the outcome. " [Collapse]

Lei LL, Ge CJ, Wang H, Fang Y, Zeng L, Wang SL, Qian MC. Application and efficacy of quetiapine in patients with high-risk factors for bipolar disorder: A randomized controlled trial. World J Psychiatry 2025; 15(8): 104221

"We are highly satisfied with the submission, peer review, and publishing process of the World Journal of Psychiatry. The online ..." [Read more]

"We are highly satisfied with the submission, peer review, and publishing process of the World Journal of Psychiatry. The online submission system was smooth and user-friendly. The peer review was timely, constructive, and objective, offering valuable feedback that significantly improved our manuscript. The editorial team ensured high-quality language editing, accurate table and figure preparation, and professional typesetting. The publication timeline was reasonable, and communication with the editorial office was prompt and clear. Overall, the process reflects the journal’s strong commitment to scientific rigor and author service. " [Collapse]

Xu CH, Hu D, Lin HJ, Yang YD, Li MN, Shao LW. Medication literacy and treatment adherence in people living with human immunodeficiency virus: Mediating effects of psychosocial factors. World J Psychiatry 2025; 15(8): 107885

"I am very pleased with what this article and others have done for the publication process, from the editorial secretariat level up ..." [Read more]

"I am very pleased with what this article and others have done for the publication process, from the editorial secretariat level up to the editor. I would also like to express my sincere gratitude to the carefully selected referees and all other staff members who contributed to this event. I will continue to write other beautiful articles and strive to get them published. " [Collapse]

Metin İ, Özdemir Ö. Artificial intelligence in medicine: Current applications in cardiology, oncology, and radiology. World J Methodol 2025; 15(4): 106854

"We sincerely appreciate the efficient and professional handling of our manuscript by the editorial team and reviewers. The submission ..." [Read more]

"We sincerely appreciate the efficient and professional handling of our manuscript by the editorial team and reviewers. The submission system was user-friendly, and the peer review process was thorough and constructive, which greatly improved our paper. The open-access model is also commendable as it maximizes the visibility of research. The editorial team demonstrated excellent communication throughout the publication process, addressing our inquiries promptly. The transparent sharing of peer review reports and editorial decisions further enhanced our confidence in the journal's rigorous standards. We are pleased with the overall experience and look forward to future collaborations with World Journal of Clinical Cases. " [Collapse]

Mei ST, Li JJ. Effective application of an innovative acemannan-enriched glycolipid sphere dressing in diabetic foot ulcer wound healing: A case report and review of literature. World J Clin Cases 2025; 13(28): 109358

"Thanks for chief editor and peer viewers and language editor. This article can be published on time because of their hard working. ..." [Read more]

"Thanks for chief editor and peer viewers and language editor. This article can be published on time because of their hard working. I truly admire your professionalism and dedication. The way you refined the language while preserving the original intent was remarkable. Your expertise not only improved the current work but also provided me with valuable insights for future writing. " [Collapse]

Xu P, Ling SS, Hu E, Yi BX. Primary signet ring cell carcinoma of the female urethra: A case report. World J Clin Cases 2025; 13(27): 107158

"I wanted to take a moment to express my appreciation for the thoroughness and dedication demonstrated by your journal. It is clear ..." [Read more]

"I wanted to take a moment to express my appreciation for the thoroughness and dedication demonstrated by your journal. It is clear that you go above and beyond to maintain high standards throughout every stage of the publication process. The level of detail and care you put into editorial and peer review reflects your strong commitment to ensuring only work of the highest quality is published. This not only upholds the reputation of the journal but also supports the advancement of the field. Thank you for your dedication to excellence. " [Collapse]

Gupta AK, Surendranath A. Cholecysto-biliary fistula mimicking type 1 Mirizzi syndrome: A case report. World J Clin Cases 2025; 13(28): 108437

"The peer review process was efficient, professional, and constructive. The reviewers provided detailed and insightful comments that ..." [Read more]

"The peer review process was efficient, professional, and constructive. The reviewers provided detailed and insightful comments that greatly improved the quality and clarity of the manuscript. The suggestions were highly relevant to the study design, data interpretation, and overall presentation. I truly appreciate the reviewers' efforts and the editorial team's timely communication throughout the process. " [Collapse]

Wang Y, Tan ZY, He JM, Shu YX, Pan Z, Zhu DG, Wang J. Novel handheld pelvic alignment guide for hollow screw fixation in osteoporotic pelvic fragility fractures. World J Orthop 2025; 16(7): 107087

"We experienced a highly efficient and well-structured peer review process with the World Journal of Gastroenterology (WJG), which ..." [Read more]

"We experienced a highly efficient and well-structured peer review process with the World Journal of Gastroenterology (WJG), which reaffirmed its stature as a respected journal in the field of medicine. This experience provided us with valuable insights into the process of scientific manuscript preparation and significantly contributed to our development as medical researchers. " [Collapse]

Kim C, Lee HS, Na HY, Kwon HJ, Lee JA, Suh YS, Kang SH, Kim HH, Ahn SH, Oh HJ. Prognostic value of signet-ring cell carcinoma proportion in undifferentiated gastric cancer: Implications for endoscopic treatment decisions. World J Gastroenterol 2025; 31(30): 109465

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your prestigious PubMed Journal. We are very much obliged for the great efforts done by the reviewers, editors and the publication team. Their actions had greatly improved the overall scientific and academic quality of our manuscript upto highest international standards. Hopefully this unique manuscript will garner lots of citation in the scientific community. Thanks for the opportunity. Best Regards, Dr . Arvind Kumar Morya MS(Gold Medalist) MNAMS Additional Professor & Unit-I Head Cataract, Glaucoma, Refractive, Squint Paediatric Ophthalmology and Medical Retina Services Associate Editor UKJOS, National Advisor IJO,GJCSRO Editorial Board Member IJOVS, WJCC, EC-Ophthalmology, DOS Times, Journal of HOS. Reviewer Elsevier, AIMDR and IJO Clinical Trial Expert Panel - CDSCO & Ministry of Health and Family Welfare Convenor - AIOS Adverse Event Committee Department of Ophthalmology All India Institute of Medical Sciences, Bibinagar Hyderabad, Telangana -508126 INDIA +91-8003996598 " [Collapse]

Morya AK, Behera RK, Gupta PC. Middle meningeal artery embolisation in chronic subdural hematoma: A double-edged sword. World J Clin Cases 2025; 13(28): 109364

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

Sinha S, Nishant P, Morya AK, Sinha RK, Singh A. Intraocular pressure variation (ocular hypertension) in diabetes mellitus. World J Clin Cases 2025; 13(28): 107263

"We, the authors, have thoroughly reviewed the final version of this manuscript and confirm its accuracy, completeness, and adherence ..." [Read more]

"We, the authors, have thoroughly reviewed the final version of this manuscript and confirm its accuracy, completeness, and adherence to the journal’s guidelines. We are fully satisfied with the content, presentation, and revisions made during the peer-review process. We appreciate the editorial team’s efforts and support and believe this work is now ready for publication in its current form. " [Collapse]

Cen YY, Nong HY, Huang XX, Lu XX, Pu CH, Huang LH, Zheng XJ, Pan ZL, Huang Y, Ding K, Huang DY. Computed tomography-based deep learning and multi-instance learning for predicting microvascular invasion and prognosis in hepatocellular carcinoma. World J Gastroenterol 2025; 31(30): 109186

"We are honored to publish a manuscript in World Journal of Gastroenterology. Both journal's credibility and journal's peer review ..." [Read more]

"We are honored to publish a manuscript in World Journal of Gastroenterology. Both journal's credibility and journal's peer review are professional and fair. To my surprise, the staff was very efficient throughout the submission process (with editor, under review, revision, decision and so on). Thanks to all editors and reviewers for their assistance throughout the publication process of this article. Best wishes to all of us. " [Collapse]

Liu Y, Xiao Y, Ai LF, Zhang JJ, Zhang JD, Qi ZQ, Dong L, Wang YD. Serum metabolomic characteristics and their predictive value for ninety-day prognosis in patients with acute-on-chronic liver failure. World J Gastroenterol 2025; 31(30): 110401

"I would like to express my sincere appreciation for the exceptionally thorough and constructive peer review process. The reviewers ..." [Read more]

"I would like to express my sincere appreciation for the exceptionally thorough and constructive peer review process. The reviewers demonstrated remarkable expertise in our field, providing insightful critiques that significantly enhanced both the scientific rigor and clarity of our manuscript. Their attention to detail helped refine key methodological aspects and strengthen the overall impact of our study. Particularly noteworthy was their ability to identify areas for improvement that we had overlooked, while respecting the study's original objectives. The editorial team deserves special recognition for their efficient coordination throughout the review process; their clear communication and prompt handling of revisions made the experience smooth and productive. This rigorous yet supportive process exemplifies why World Journal of Gastroenterology maintains high standards in our field. I am truly grateful for the opportunity to contribute to your esteemed journal. " [Collapse]

Zeng XL, Zhu LJ, Zhang Y, Yang XD, Zhu YJ. Unveiling Xuanshen decoction: A novel approach to combat slow transit constipation. World J Gastroenterol 2025; 31(30): 109187

"Sincere thanks to the editorial department and the publishing house.From the submission of the initial draft to the final ..." [Read more]

"Sincere thanks to the editorial department and the publishing house.From the submission of the initial draft to the final publication,the editors have always treated my manuscript with a rigorous and meticulous attitude.The peer review was highly objective and provided substantial assistance for my article.The F6Publishing system is very smooth to use. " [Collapse]

Sun YT, Zhou F, Zheng HX, Xiao JD. Clinical efficacy and mechanism of Bletilla striata and Chinese herbal compounds in treatment of peptic ulcer. World J Gastroenterol 2025; 31(30): 110145

"As the authors, we believe this case report highlights the potential of ultrasound-guided platelet-rich plasma (PRP) injections in ..." [Read more]

"As the authors, we believe this case report highlights the potential of ultrasound-guided platelet-rich plasma (PRP) injections in managing post-traumatic lumbar myofascial pain syndrome. The comprehensive assessments conducted throughout the study validate the notable improvements in pain relief, functional recovery, and restored muscle symmetry, while the detailed 6-month follow-up data further support the reliability of our findings. We would like to express our sincere gratitude to the editorial team for their meticulous handling of our manuscript and to the reviewers for their insightful and constructive comments. Their professional guidance has been invaluable in refining the presentation of this innovative intervention, helping us strengthen the scientific rigor of our work and ensuring it contributes meaningfully to the field of myofascial pain syndrome research. " [Collapse]

Ai SL, Xiang XN, Yu X, Li N, Zhang XY, Zhang KB, Jiang HY, Wang Q, He HC. Ultrasound-guided platelet-rich plasma injection improves pain, function and symmetry in lumbar myofascial pain syndrome: A case report. World J Clin Cases 2025; 13(27): 108998

"The peer review during this submission process was highly efficient and provided me with review comments very quickly. The editor ..." [Read more]

"The peer review during this submission process was highly efficient and provided me with review comments very quickly. The editor is also very conscientious and responsible. The responses to emails are very timely and accurate. I hope that if there are suitable manuscripts next time, they can also be published in this journal. " [Collapse]

Wang GC, Chen JX, Pan HF, Ye K, Guo YC, Huang Y. Long-term efficacy and short-term outcomes of intersphincteric resection vs abdominoperineal resection in patients with ultra-low rectal cancer. World J Gastroenterol 2025; 31(29): 110004

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

Kaur R, Morya AK, Gupta PC, Aggarwal S, Menia NK, Kaur A, Kaur S, Sinha S. Artificial intelligence-based apps for screening and diagnosing diabetic retinopathy and common ocular disorders. World J Methodol 2025; 15(4): 107166

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your prestigious PubMed Journal. We are very much obliged for the great efforts done by the reviewers, editors and the publication team. Their actions had greatly improved the overall scientific and academic quality of our manuscript upto highest international standards. Thanks for the opportunity. Best Regards, Dr . Arvind Kumar Morya MS(Gold Medalist) MNAMS Additional Professor & Unit-I Head Cataract, Glaucoma, Refractive, Squint Paediatric Ophthalmology and Medical Retina Services Associate Editor UKJOS, National Advisor IJO,GJCSRO Editorial Board Member IJOVS, WJCC, EC-Ophthalmology, DOS Times, Journal of HOS. Reviewer Elsevier, AIMDR and IJO Clinical Trial Expert Panel - CDSCO & Ministry of Health and Family Welfare Convenor - AIOS Adverse Event Committee Department of Ophthalmology All India Institute of Medical Sciences, Bibinagar Hyderabad, Telangana -508126 INDIA +91-8003996598 " [Collapse]

Nishant P, Singh A, Morya AK, Alam MA, Sinha S. Manual small incision cataract surgery: An ergonomic solution to tackle cataract backlog and challenging situations. World J Methodol 2025; 15(4): 104529

"We have read the online full-text article. We are satisfied with the editing quality of the article, the published articles processes, ..." [Read more]

"We have read the online full-text article. We are satisfied with the editing quality of the article, the published articles processes, the rigorous review process and the patient communication of World Journal of Gastroenterology. We will continue to submit new manuscripts in the future and recommend our peers to contribute manuscripts. " [Collapse]

Zhang L, Bai CZ, Shan JY, Xue HL, Zheng SM, Chen YL, Tang SH. Flotillin-1 promotes the progression of hepatocellular carcinoma by activating TFE3-mediated Golgi stress response via inhibition of mTORC1/2. World J Gastroenterol 2025; 31(29): 106895

19226 items Read more >>

Article Quality Tracking-Peer-Review

"ESD is a very effective procedure for early-stage gastric cancer, but there are cases where metastasis occurs. The author ..." [Read more]

"ESD is a very effective procedure for early-stage gastric cancer, but there are cases where metastasis occurs. The author scientifically examined many cases and came to the following conclusions, making this a very good paper. A higher SRCC proportion is associated with smaller tumor size, less advanced T stages, fewer nodal or distant metastases, and reduced lymphatic, venous, and neural invasion. Particularly, the SRCC proportion in EGC should be validated as a significant factor in therapeutic approaches, including ESD. " [Collapse]

"The letter to the editor by Dimirli Atici S et al entitled "Integrating inflammation, nutrition, and artificial intelligence: A new ..." [Read more]

"The letter to the editor by Dimirli Atici S et al entitled "Integrating inflammation, nutrition, and artificial intelligence: A new era in colorectal cancer prognostic scoring" World J Gastroenterol 2025; 31(30): 108431 [DOI: 10.3748/wjg.v31.i30. 108431] discusses a critical issue for the coming years. These methods can help improve the prediction of survival in patients with CRC by increasing the rate of application of personalized treatments. The method discussed by the authors involves the integration of biochemical markers with artificial intelligence and is expected to significantly improve the quality of therapeutic decisions, thereby improving patient outcomes. Medical science is a field in which artificial intelligence already offers a lot, and is expected to offer even more in the coming years. Of course, it is not likely to replace the decisions of the therapeutic team responsible for managing patients with CRC, but it will significantly help in making the right decisions. In my opinion, the period we are currently experiencing is likely to be a milestone for the future of medical science. " [Collapse]

Demirli Atici S, Canda AE, Terzi MC. Integrating inflammation, nutrition, and artificial intelligence: A new era in colorectal cancer prognostic scoring. World J Gastroenterol 2025; 31(30): 108431

"In this manuscript, the authors aimed to clarify the efficacy of measuring core-fucosylated low-molecular-weight kininogen (LMWK-Fc) ..." [Read more]

"In this manuscript, the authors aimed to clarify the efficacy of measuring core-fucosylated low-molecular-weight kininogen (LMWK-Fc) for screening patients with liver fibrosis from normal volunteers. Although the performance in distinguishing between cases with and without fibrosis is largely affected by the distribution of fibrosis levels in patients with liver diseases, no data are provided showing this distribution. While the authors claimed that the correlation between LMWK-Fc and liver stiffness values was significant, the correlation coefficient was relatively low at 0.5789. The authors should demonstrate the distribution of this correlation by plotting the relationship. It would be difficult to utilize an indicator with a correlation coefficient of only 0.58. Furthermore, the authors attempted to establish the significance of LMWK-Fc by comparing its performance with other indicators, specifically gamma-glutamyl transferase and alkaline phosphatase, which are not established indicators for liver fibrosis. Therefore, it is difficult to confirm the efficacy of LMWK-Fc in evaluating liver fibrosis. Additionally, even if higher LMWK-Fc values result from the biological processes of fibrosis, these values may not indicate in which organ the fibrosis is occurring. Combined with poor English throughout (such as in the descriptions in the first paragraph of the introduction section), this manuscript may not provide useful information for the evaluation of liver fibrosis. " [Collapse]

Gao GF, Yu J, Tong L, Jiang D. Predictive value of core-fucosylated low-molecular-weight kininogen levels in patients with liver fibrosis: A prospective study. World J Gastroenterol 2025; 31(29): 105210

"The study addresses the limitations of current diagnostic and surveillance methods for papillary thyroid cancer (PTC)—such as ..." [Read more]

"The study addresses the limitations of current diagnostic and surveillance methods for papillary thyroid cancer (PTC)—such as ultrasound, FNA, and thyroglobulin—and evaluates circulating miRNAs (miR-146, miR-221, miR-222) as promising non-invasive biomarkers. The authors followed PRISMA guidelines and used a clear flow diagram (Figure 1). Study quality was assessed using the QUADAS-2 tool, which is appropriate for diagnostic accuracy reviews (Table 3). The study separately evaluates PTC vs benign nodules and benign nodules vs healthy controls. This includes sensitivity, specificity, and false-positive rates for each miRNA, and highlights that miR-146 is most sensitive and miR-222 is most specific. Limitations Limited Number of Included Studies (n=6): Only six studies were included in the meta-analysis, with one from Europe and the rest from Asia. This raises concerns about geographic bias and limited generalizability. Methodological Heterogeneity: All studies used different platforms for miRNA quantification (e.g., qPCR, microarray), leading to an “unclear risk” rating in the index test domain of QUADAS-2 for all included studies. " [Collapse]

Dean B, Geropoulos G, Richardson-Jones T, Fornasiero M, Papapanou M, Konstantinidis C, Madouros N, Spinos D, Koimtzis G, Giannis D, Athanasiou C, Psarras K. Diagnostic accuracy of circulating miR-146, miR-221 and miR-222 in papillary thyroid cancer: A systematic review and meta-analysis. World J Clin Cases 2025; 13(27): 104916

"Thisa isa an excellant start to a full review of this topic. I suggest you consider perfrorming a systematic review to add to the ..." [Read more]

"Thisa isa an excellant start to a full review of this topic. I suggest you consider perfrorming a systematic review to add to the literature, and update clinical scientists and clinicians. Perhaps you could direct your topic towrds "How therapies for inflammatory bowel disease are tailored based on the pdiffering pathogenesis of Crohn's disease and ulcerative colitis." [Collapse]

Agrawal H, Gupta N. Comparative analysis of the pathogenesis in Crohn’s disease and ulcerative colitis. World J Gastroenterol 2025; 31(29): 109892

"1. The typical sites of involvement can be mentioned- sole, scalp, back 2. The drug of choice can be mentioned with dosing, ..." [Read more]

"1. The typical sites of involvement can be mentioned- sole, scalp, back 2. The drug of choice can be mentioned with dosing, frequency 3. A characteristic histopathology / photomicrograph can be included for better understanding 4. Those with HIV positivity can have adverse drug reaction / toxicity due to sulfonamides, may require alternatives 5. Other common differentials can be listed - Actinomycosis, sporotrichosis" [Collapse]

Nagoba BS, Dhotre SV, Gavkare AM, Mumbre SS, Dhotre PS. Cutaneous nocardiosis in chronic renal insufficiency: Diagnostic and therapeutic considerations. World J Clin Cases 2025; 13(26): 108211

"1. What were the differentials after clinical examination? 2. Was there a change in weight / significant weight loss / anorexia? 3. ..." [Read more]

"1. What were the differentials after clinical examination? 2. Was there a change in weight / significant weight loss / anorexia? 3. Were the bowel loops displaced by the mass? Any great vessel encasement noted on imaging? Was the mass well encapsulated on imaging and intra op? 4. What is the evidence to consider the diagnosis of Liposarcoma rather than lipoma? 5. What was the dose of adjuvant RT?" [Collapse]

Cheng LL, Tang B, Liu H, Zhu F, Chen YF, Zhang W. Thoughts and challenges of giant retroperitoneal liposarcoma: A case report. World J Clin Cases 2025; 13(26): 108308

"1. Were all malignant lesions considered? 2. How were infective causes such as infective / viral myocarditis ruled out? 3. Were ..." [Read more]

"1. Were all malignant lesions considered? 2. How were infective causes such as infective / viral myocarditis ruled out? 3. Were the groups evaluated for significant difference in age? 4. Was the maximum tolerable dose limit exceeded in the cases? 5. The numbers do not tally - "the final sample comprised 194 patients." The table shows 195 pts 6. What were the study limitations?" [Collapse]

Méndez-Toro A, Muñoz-Rossi FA, Tejada-Cabrera RE, Rojas-Ruiz IT, Flechas-Ardila JD, García-Gutiérrez A, Novoa-Álvarez RA. Monitoring high-risk patients for chemotherapy-related cardiotoxicity: A retrospective analysis. World J Clin Cases 2025; 13(26): 107716

"1. Did the pt undergo periodic cystoscopy evaluation as part of the follow up? 2. Was a lesser radical procedure considered, given ..." [Read more]

"1. Did the pt undergo periodic cystoscopy evaluation as part of the follow up? 2. Was a lesser radical procedure considered, given the size of the lesion, lack of local spread, and the age? 3. Did the pt satisfactorily complete adjuvant therapy the first time , 10 years back? 4. Any other options available which can reduce the chance of second malignancy - continent heterotopic pouch / colonic patch aument? " [Collapse]

Murakami M, Noguchi H, Matsushita R, Tatarano S, Kirishima M, Tasaki T, Kitazono I, Higashi M, Enokida H, Tanimoto A. Urothelial carcinoma arising in orthotopic ileal neobladder reconstruction: A case report. World J Clin Cases 2025; 13(26): 104876

"1. The small sample size is a limitation 2. The assessment can be included as an objective parameter 3. The inclusion / exclusion ..." [Read more]

"1. The small sample size is a limitation 2. The assessment can be included as an objective parameter 3. The inclusion / exclusion criteria can be more elaborate 4. Exclusion of relevant psychiatric / somatic disorders to be included 5. Was use of medication / drugs considered as a subgroup analysis? 6. Were age, gender confounding factors in the study? " [Collapse]

Jeong HW, Jung JW, Jang SH, Kim DY, Lee JY, Jang JS. Effects of driving simulator intervention on post-traumatic stress disorder symptoms after traffic accidents: A single-subject study. World J Clin Cases 2025; 13(26): 100363

"The need for the development of non-invasive tests in chronic hepatitis of either etiology is necessary. The power and limitations ..." [Read more]

"The need for the development of non-invasive tests in chronic hepatitis of either etiology is necessary. The power and limitations of the study conducted by Peta et al. are discussed well in this letter. To reach the targets of individualized medicine in AIH, the patient's multi omics data should be integrated in the upcoming assessment models. " [Collapse]

Jerez Diaz D, Twohig P. Toward non-invasive assessment strategies in autoimmune hepatitis. World J Hepatol 2025; 17(7): 107881

"This is an interesting case report. Autoimmune diseases might be seen in CLL. Although the patient has no risk factor for viral ..." [Read more]

"This is an interesting case report. Autoimmune diseases might be seen in CLL. Although the patient has no risk factor for viral hepatitis, I check the viral load in such a case. Diagnosing the viral hepatitis by measuring the antibody levels could be misleading in CLL. Moreover, there is no data regarding the serum HBc antibody level in this case. Biochemical response include the normalization of gamma globulin level and serum IgG levels (No data was provided in this report). I would be glad if there was long term follow up data including the histologic response." [Collapse]

Giacomelli M, Carotti S, Vozella F, Pagliei F, Taffon C, Baiocchini A, Gambaro FL, Picardi A, Vespasiani-Gentilucci U, Galati G. Autoimmune hepatitis with syncytial giant cells in chronic lymphocytic leukemia: A case report and literature review. World J Hepatol 2025; 17(7): 106253

"In this editorial manuscript, the authors summarize both established and experimental endoscopic approaches aimed at improving ..." [Read more]

"In this editorial manuscript, the authors summarize both established and experimental endoscopic approaches aimed at improving metabolic states in metabolic dysfunction-associated fatty liver disease. These approaches target pathways such as the gut-islet axis, gut-brain axis, intestinal microbiota and its metabolites, as well as mechanisms involving nutrient restriction and malabsorption. The procedures are concisely described, with particular emphasis on a key study involving duodenal mucosal ablation using electroporation. In addition to discussing the efficacy of each method, the authors' presentation of limitations and future directions is informative and valuable. " [Collapse]

Fernandez CJ, Jena S, Lakshmi V, Pappachan JM. Duodenal mucosal ablation: An emerging therapeutic concept for metabolic dysfunction-associated fatty liver disease. World J Gastroenterol 2025; 31(28): 109468

"Indeed, with liver cirrhosis, both morphofunctional restructuring of the hepatic vasculature and complex splanchnic and systemic ..." [Read more]

"Indeed, with liver cirrhosis, both morphofunctional restructuring of the hepatic vasculature and complex splanchnic and systemic hemodynamic disturbance occur, contributing to the development of severe complications. In children, due to the rarity of liver cirrhosis, these disorders are rare, and therefore, the number of publications is small. I read with interest the article by Tambucci et al. The authors presented a well-structured review based on the current understanding of this pressing issue." [Collapse]

Tambucci R, Stephenne X, Channaoui A, de Magnée C. Liver and systemic hemodynamics in cirrhotic children. World J Hepatol 2025; 17(7): 103179

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohn’s disease. In recent years, it has been ..." [Read more]

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohn’s disease. In recent years, it has been reported that improving the intestinal flora improves liver damage. This is very interesting data, and it is believed that improving the intestinal flora improves bile acids and liver function. Please explain the mechanism behind this." [Collapse]

Ma L, Zhang MH, Xu YF, Hao YX, Niu XX, Li Y, Xing HC. Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease. World J Gastroenterol 2025; 31(28): 105089

"The article “Stem cell therapy for diabetes: Advances, prospects, and challenges” provides a concise and informative overview of ..." [Read more]

"The article “Stem cell therapy for diabetes: Advances, prospects, and challenges” provides a concise and informative overview of current developments in stem cell–based approaches to treating diabetes, with a particular focus on induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and pancreatic islet transplantation. Zuo et al. present the current state of research, acknowledging both the exciting advancements and the persistent challenges. However, in some cases, the discussion leans toward emphasizing successful studies and positive trial outcomes, occasionally lacking a rigorous critique of failures or contradictory findings in the field. Thus, many of the cited studies report favorable outcomes, with limited discussion of trials that yielded null results or failed to translate to clinical efficacy. Authors clearly explain the underlying biological mechanisms, such as β-cell differentiation and paracrine immunomodulation by MSCs. Noteworthy advances are documented, including CRISPR-mediated immune evasion strategies, the development of encapsulation technologies to protect transplanted cells from host immunity, and the application of bioprinting to improve islet viability and function. The authors effectively describe the transition from basic research to clinical application, citing the first-in-human trials and the survival of stem cell–derived islets for over one year in patients. These contributions add clarity and momentum to the translational landscape of regenerative diabetes therapies. Authors also acknowledges unresolved issues that remain major barriers to clinical translation. These include the risks of tumorigenicity associated with iPSCs, the low engraftment efficiency of transplanted cells, and ongoing challenges with host immune rejection. Furthermore, the absence of long-term safety and efficacy data from randomized controlled trials highlights the need for more rigorous evidence before widespread adoption. The authors propose future directions such as 3D bioprinting of organoids, AI-guided combination therapies, and further refinement of genome editing techniques to enhance safety and immune compatibility. In conclusion, this review offers a well-informed and timely synthesis of the rapidly evolving field of stem cell therapy for diabetes. It successfully highlights promising technologies and recent clinical breakthroughs while acknowledging the complexity of translating laboratory innovations into durable, safe, and accessible therapies. Future iterations of this work would benefit from deeper critical analysis of contradictory evidence, expanded discussion on regulatory and ethical frameworks, and integration of emerging clinical trial data. Such enhancements would further strengthen its contribution to the scientific community and aid in shaping the direction of next-stage research and therapeutic development." [Collapse]

Zuo DB, Wang CH, Sang M, Sun XD, Chen GP, Ji KK. Stem cell therapy for diabetes: Advances, prospects, and challenges. World J Diabetes 2025; 16(7): 107344

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial ..." [Read more]

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial chemoembolization (TACE) and microwave ablation (MWA) have an adverse events, and so authors should make clear the definition of hepatic hemangioma which needs treatment. Authors only described the prognosis after 12 months. Authors should report the longer prognosis. " [Collapse]

Sun JP, Zhou K, Pan J, Yang N, Sun XN, Zhao HT, Yang XB. Efficacy and safety of transcatheter arterial chemoembolization combined with microwave ablation for hepatic hemangiomas (> 5 cm). World J Gastroenterol 2025; 31(28): 109078

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in ..." [Read more]

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in this age group, diagnosis, treatment options and therapeutic considerations, public health challenges and future implications. Specific mention of differential diagnostic consideration is also appreciated. Reference list is relevant and complete and the quality of language is good. Although I understand that MPox is rare in children, I'd suggest if possible to add some statements on the current epidemiology of MPox in this age group, or if it is only limited to case reports. " [Collapse]

Ikram E, Shaukat A, Qureshi MS, Saifullah M, Aslam MA, Mehdi AM. Monkeypox in neonates: A narrative review on clinical presentations, vertical transmission, and treatment challenges. World J Clin Infect Dis 2025; 14(1): 109806

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ ..." [Read more]

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ and preventing the entry of H+ into the gastric lumen. Existing studies demonstrate that VPZ-based treatment regimens, including triple therapy regimens with VPZ, amoxicillin, and clarithromycin, are both safe and effective in eradicating H. pylori. The multicenter randomized controlled trial discussed here was the first to compare triple therapy based on VPZ (VPZ/amoxicillin/clarithromycin) with the 14-day quadruple regimen based on bismuth in China. The results showed that triple therapy with VPZ achieved higher eradication rates compared to the quadruple regimen and with similar rates of side effects, making triple therapy with VPZ an important alternative (without bismuth) for eradicating H. pylori. Interestingly, no significant differences in eradication rates were observed between the 10- and 14-day treatments. However, to optimize results and reduce the incidence of antibiotic resistance, it is necessary to conduct extensive, multicenter studies in various countries worldwide." [Collapse]

Han RS, Hao JW, Wang T, Xin Z, Fan GX, Wang GD, Liu MM, Liu CX, Yang QZ, Yang ZW, Lv XY, Zhang C, Bian G, Meng J, Cui ZQ, Yun XJ, Cao JH, Li SH, Fan JF, Ma HG, Gao FY, Mao T, Tian ZB, Song XH, Yu YN. Efficacy and safety of triple therapy with vonoprazan for Helicobacter pylori eradication: A multicenter, prospective, randomized controlled trial. World J Gastroenterol 2025; 31(28): 109001

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the ..." [Read more]

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the role of tumor microenvironment in the immune invasion, therapy resistance and metastasis process in Breast cancer. This understanding will definitely help us to explore the breast cancer progression with new therapeutic approach. The minireview is well written and beautifully presented. The language and grammar is appropriate. The referencing is good. However, a description on role of tumor microenvironment on angiogenesis and angiogenic signaling could have been discussed. Overall The review is good and useful for the scientific community." [Collapse]

Çakal S, Er Urgancı B, Şimşek S. Key players in the breast cancer microenvironment: From fibroblasts to immune cells. World J Clin Oncol 2025; 16(7): 107339

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2265

Peer-reviewers: 32829

Manuscripts received today: 23

Manuscript reviews today: 46

Unhandled manuscripts today: 127

Active peer-reviewers today: 1631

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